ELECTROSPUN NANOFIBERS FOR TISSUE ENGINEERING APPLICATIONS
Ling Ling Tian
Singapore Institute for Neurotechnology, Singapore National University of Singapore, Singapore
Electrospinning, with the advantages of wide ranges of applicable biocompatible polymers and tunable physio-chemical properties of the final products, is a straightforward and low-cost technique for the fabrication of nanofibrous scaffolds for tissue engineering applications. Diverse polymers including sythetic polymer PLA, PCL, PLGA, PLACL, etc and natural polymer collagen, gelatin, chitosan, etc have been electrospun into nanofibrous scaffolds with various forms such as random fibers, aligned fibers, 3D fibrous scaffold and core-shell fibers, which could be applied for nerve, bone, cardiac, vascular tissue engineering applications. The diversity and versatility of electrospinning technique, together with functionalizing cues (such as growth factors), conductive polymers, and stem cells have gained considerable success for tissue engineering applications.