ACOUSTICAL DROPLET FLUIDICS: HIGHTHROUGHPUT MANIPULATION OF CELLS AND DROPS
University of Glasgow, UK
The use of acoustics in microfluidics has become very popular for the past few years because it provides an extremely versatile tool to manipulate small amounts of fluid on a chip in a highly controlled manner. Mixing, pumping, focusing and deflection has been successfully demonstrated and already included in commercial available products.
Here, we present the power of surface acoustic wave driven microfluidics for droplet fluidics. We have developed a surface acoustic wave (SAW) driven microchannel drop-maker that can generate pressures up to 2 kPa and apply this to control the size of droplets produced in a microfluidic crossjunction dropmaker in real time at high speed.
Moreover, we show other useful operation that can be carried out on our hybrid acoustofluidic platform including high-throughput sorting of cells and drops as well as merging, trapping and pumping in closed looped channels.