3D ORIGAMI PHOTONIC CRYSTALS PAPER-LIKE µPADS
Bing Bing Gao
Southeast University, China
POCT(point-of-care testing) has attracted broad attention recently. Microfluidic chip based on paper is one of the most potential strategy to realize POCT. Recently traditional paper chips presented insignificance as unable to quantify, low sensitivity. We developed a microfluidic origami PCs paperlike µPADs based on blade-coating pattern strategy nitrocellulose inverse opal and it consists of two simple steps: (1) Printing on a PP plastic film to form hollow channels or patterns using a HP laser printer then blade coating of colloidal SiO2 nanoparticles with different diameters on the film to form patterned photonic crystals. (2) Nitrocellulose prepolymers were then immersed in the photonic crystals patterns, after baking on a hot plate and etching using HF the inverse opal nitrocellulose film was made. We used this method for fabricating microfluidic origami PCs paper-like µPADs for detection human IgG. We also fabricated PCs µPADs based on this for small molecule compounds detection.