C3: Computational Bioengineering II


Shubham Thosar1, Pratik Naik

1Jawaharlal Nehru Engineering College, India

Carotid Artery Aneurysm is a diseased condition which results in a bulging out of the weaker area of carotid artery. Aneurysm possesses the risk of breakage which may lead to brain hemorrhage or stroke. Hence, patient specific numerical study to understand this disease progression is important. In this paper, we present a Fluid-Structure Interaction (FSI) method to numerically investigate the hemodynamics of a compliant patient specific carotid artery bifurcation model. A partitioned based strongly coupled two-way approach is used to separately interact the fluid solver and structural solver. Galerkin Finite Element Method is used to solve Navier Stokes Equation while an Arbitrary Lagrangian Eulerian (ALE) formulation is used to predict the mesh movement.  Newmark scheme was employed to solve the dynamic equilibrium equations for linear elastic solid arterial wall. Blood was modeled as pulsatile, cyclic and Non-Newtonian fluid using Carreau model while the arterial wall is assumed to be linearly elastic, isotropic and incompressible. The role of flexible arterial wall thickness and wall material stiffness on the dynamics of the blood flow is investigated. The significance of wall shear stress, arterial wall deformation, velocity contours and pressure variation across the artery length are studied at the bifurcation and at critical locations such as aneurysm. The results obtained matches adequately with the general flow pattern observed in literature. In conclusion, this study shows the importance of numerical methods to study patient specific hemodynamics of arterial blood flow to better understand the disease progression.

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